Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz

نویسندگان

  • A. G. Markelz
  • A. Roitberg
  • E. J. Heilweil
چکیده

We report the first use of pulsed terahertz spectroscopy to examine low-frequency collective vibrational modes of biomolecules. Broadband absorption increasing with frequency was observed for lyophilized powder samples of calf thymus Ž y1. DNA, bovine serum albumin and collagen in the 0.06–2.00 THz 2–67 cm frequency range, suggesting that a large number of the low-frequency collective modes for these systems are IR active. Transmission measurements at room temperature showed increasing FIR absorption with hydration and denaturing. q 2000 Published by Elsevier Science B.V. All rights reserved.

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تاریخ انتشار 2000